- The rapid increase in cardiovascular disease determinants,
such as ageing, smoking, obesity and sedentary lifestyles are transforming healthcare needs in developing countries
- Global cardiovascular non-adherence rates are greater than 50% in developing countries, indicating a significant opportunity to improve healthcare outcomes
- Low cardiovascular medication adherence is associated with significantly worse outcomes, including increased risk of mortality, morbidity and healthcare costs
- Physicians can use a number of simple and efficient strategies to increase adherence
Cardiovascular Diseases Are Transforming Healthcare Needs.
Changing demographics and lifestyle trends are driving an unprecedented increase in the prevalence of chronic conditions, affecting nearly half of all adults and approximately 8% of children worldwide.1 Cardiovascular diseases pose a particular threat as the leading cause of mortality globally, and disproportionately affecting low- and middle-income countries.2 Cardiovascular disease determinants, such as population ageing, smoking and obesity, are manifesting dramatically in these countries.
For example, the proportion of the population over age 65 is expected to double in just two decades in Brazil, a phenomenon which took over a century in France.3 Amid these shifts, pharmacological treatments are increasingly important as effective disease management solutions but require adherence to be effective.
Non-adherence Among Cardiovascular Patients Is Significant, Even After Acute Events.
Adherence rates for cardiovascular treatments generally approximate the global adherence rate of 50%, meaning that roughly half of prescribed medications are not taken.4,5 Other studies indicate that adherence rates are even lower in developing countries.6 Even acute cardiac events do not necessarily improve adherence. Adherence rates are poor even among patients who have experienced an acute cardiac event. In a study of more than 4,500 post-myocardial infarction (MI) patients, 18% did not once fill their cardiac medications in the 4 months after discharge from hospital. And in a separate cohort of more than 22,000 post-acute coronary syndrome patients, 60% discontinued their statin medication within 2 years of hospitalization (non-persistence).7